Manchester Bioinference
Manchester Bioinference
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CellTypeAI: Automated cell identification for scRNA-seq using local generative-AI
Rufus H. Daw
,
Harry R. Deijnen
,
Magnus Rattray
,
John R. Grainger
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DOI
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Integration of unpaired and heterogeneous clinical flow cytometry data
Mike Phuycharoen
,
Verena Kaestele
,
Thomas Williams
,
Lijing Lin
,
Tracy Hussell
,
John Grainger
,
Magnus Rattray
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DOI
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Glucocorticoid-dependence and independence of the circadian liver transcriptome
The liver, a key metabolic organ, shows clear day-night variation in gene and protein expression, and in metabolic pathway activity. …
\Robert J\ Maidstone
,
\A Louise\ Hunter
,
Mudassar Iqbal
,
Nicola Begley
,
Matthew Baxter
,
\Andrew S I\ Loudon
,
Magnus Rattray
,
\David W\ Ray
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DOI
One-Hot News: Drug Synergy Models Shortcut Molecular Features
Emine Beyza Çandır
,
Halil İbrahim Kuru
,
Magnus Rattray
,
A Ercument Cicek
,
Oznur Tastan
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DOI
URL
Genomic foundation models reveal RNA-binding proteins regulating translation and mRNA degradation during Drosophila development
Logan Brase
,
Declan R. Creamer
,
Yuliya Shapovalova
,
Mark P. Ashe
,
Hilary L. Ashe
,
Magnus Rattray
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DOI
URL
Decoding the Spatial and Epigenetic Logic of Early Skin Development
Nigel L. Hammond
,
Syed Murtuza Baker
,
Amanda McGovern
,
Antony Adamson
,
Andrew D Sharrocks
,
Magnus Rattray
,
Jill Dixon
,
Michael J. Dixon
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URL
From Discovery to Delivery: A Rapid and Targeted Proteomics Workflow for Monitoring Chinese Hamster Ovary Biomanufacturing
Chinese hamster ovary (CHO) cells are the industrial workhorse for manufacturing biopharmaceuticals, including monoclonal antibodies. …
Charles Eldrid-Otterburn
,
Ellie Hawke
,
Kathleen Cain
,
Kate Meeson
,
Joanne Watson
,
Reynard Spiess
,
William Smith
,
Matthew Russell
,
Robyn Hoare
,
\John A.\ Raven
,
Jean-Marc Schwartz
,
Magnus Rattray
,
Leon Pybus
,
Alan Dickson
,
Andrew Pitt
,
Perdita Barran
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DOI
Cell–ECM Graphs: A Graph-Based Method for Joint Analysis of Cells and the Extracellular Matrix
M. Ghafoor
,
JE. Parkinson
,
T. Pham
,
TE. Sutherland
,
M. Rattray
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DOI
URL
Spatial gene regulatory networks driving cell state transitions during human liver disease
Liver fibrosis is a major cause of death worldwide. As a progressive step in chronic liver disease, fibrosis is almost always diagnosed …
\Nigel L\ Hammond
,
\Syed Murtuza\ Baker
,
Sokratia Georgaka
,
Ali Al-Anbaki
,
Elliot Jokl
,
Kara Simpson
,
Rosa Sanchez-Alvarez
,
\Varinder S\ Athwal
,
Huw Purssell
,
\Ajith K\ Siriwardena
,
\Harry v M\ Spiers
,
\Mike J\ Dixon
,
\Leoma D\ Bere
,
\Adam P\ Jones
,
\Michael J\ Haley
,
\Kevin N\ Couper
,
Nicoletta Bobola
,
\Andrew D\ Sharrocks
,
\Neil A\ Hanley
,
Magnus Rattray
,
\Karen Piper\ Hanley
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DOI
Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells
Kate E. Meeson
,
Joanne Watson
,
Susan Rosser
,
Ellie Hawke
,
Andrew Pitt
,
Tessa Moses
,
Leon Pybus
,
Magnus Rattray
,
Alan J. Dickson
,
Jean‐Marc Schwartz
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