Manchester Bioinference
Manchester Bioinference
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CellPie : a scalable spatial transcriptomics factor discovery method via joint non-negative matrix factorization
Sokratia Georgaka
,
William Geraint Morgans
,
Qian Zhao
,
Diego Sanchez Martinez
,
Amin Ali
,
Mohamed Ghafoor
,
Syed Murtuza Baker
,
Robert G Bristow
,
Mudassar Iqbal
,
Magnus Rattray
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DOI
URL
Exploiting the SunTag system to study the developmental regulation of mRNA translation
Alastair Pizzey
,
Catherine Sutcliffe
,
Jennifer C. Love
,
Emmanuel Akabuogu
,
Magnus Rattray
,
Mark P. Ashe
,
Hilary L. Ashe
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DOI
URL
Multi-omics analysis in primary T cells elucidates mechanisms behind disease-associated genetic loci
BACKGROUND: Genome-wide association studies (GWAS) have uncovered the genetic basis behind many diseases and conditions. However, most …
Chenfu Shi
,
Danyun Zhao
,
Jake Butler
,
Antonios Frantzeskos
,
Stefano Rossi
,
James Ding
,
Carlo Ferrazzano
,
Charlotte Wynn
,
\Ryan Malcolm\ Hum
,
Ellie Richards
,
Muskan Gupta
,
Khadijah Patel
,
\Chuan Fu\ Yap
,
Darren Plant
,
Richard Grencis
,
Paul Martin
,
Antony Adamson
,
Stephen Eyre
,
John Bowes
,
Anne Barton
,
Pauline Ho
,
Magnus Rattray
,
Gisela Orozco
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DOI
Spatially regulated mRNA decay sharpens expression patterns in the Drosophila embryo
Jennifer C Love
,
Lauren Forbes Beadle
,
Catherine Sutcliffe
,
Magnus Rattray
,
Hilary L Ashe
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DOI
URL
Transferability of Single- and Cross-Tissue Transcriptome Imputation Models Across Ancestry Groups
Transcriptome-wide association studies (TWAS) investigate the links between genetically regulated gene expression and complex traits. …
Inti Pagnuco
,
Stephen Eyre
,
Magnus Rattray
,
Andrew Morris
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DOI
Scalable Multi-Output Gaussian Processes with Stochastic Variational Inference
The Multi-Output Gaussian Process (MOGP) is a popular tool for modelling data from multiple sources. A typical choice to build a …
Xiaoyu Jiang
,
Sokratia Georgaka
,
Magnus Rattray
,
\Mauricio A.\ Álvarez
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Extracellular matrix phenotyping by imaging mass cytometry defines distinct cellular matrix environments associated with allergic airway inflammation
J E Parkinson
,
M Ghafoor
,
R J Dodd
,
H E Tompkins
,
M Fergie
,
M Rattray
,
J E Allen
,
T E Sutherland
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DOI
URL
GPMelt: A hierarchical Gaussian process framework to explore the dark meltome of thermal proteome profiling experiments
Cecile Le Sueur
,
Magnus Rattray
,
Mikhail Savitski
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DOI
URL
Identification of differences in CD4+ T-cell gene expression between people with asthma and healthy controls
Functional enrichment analysis of genome-wide association study (GWAS)-summary statistics has suggested that CD4+ T-cells play an …
Mauro Tutino
,
Jenny Hankinson
,
Clare Murray
,
Lesley Lowe
,
Gina Kerry
,
Magnus Rattray
,
Adnan Custovic
,
\Sebastian L.\ Johnston
,
Chenfu Shi
,
Gisela Orozco
,
Stephen Eyre
,
Paul Martin
,
Angela Simpson
,
\John A.\ Curtin
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DOI
SynBa: improved estimation of drug combination synergies with uncertainty quantification
Haoting Zhang
,
Carl Henrik Ek
,
Magnus Rattray
,
Marta Milo
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DOI
URL
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